Integrated analyses of murine breast cancer models reveal critical parallels with human disease

Mouse models have an essential role in cancer research, yet little is known about how various models resemble human cancer at a genomic level. Here, we complete whole genome sequencing and transcriptome profiling of two widely used mouse models of breast cancer, MMTV-Neu and MMTV-PyMT. Through integ...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Rennhack, Jonathan P., To, Briana, Swiatnicki, Matthew, Dulak, Caleb, Ogrodzinski, Martin P., Zhang, Yueqi, Li, Caralynn, Bylett, Evan, Ross, Christina, Szczepanek, Karol, Hanrahan, William, Jayatissa, Muthu, Lunt, Sophia Y., Hunter, Kent, Andrechek, Eran R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6646342/
https://ncbi.nlm.nih.gov/pubmed/31332182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11236-3
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