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Low E2F2 activity is associated with high genomic instability and PARPi resistance
The E2F family, classically known for a central role in cell cycle, has a number of emerging roles in cancer including angiogenesis, metabolic reprogramming, metastasis and DNA repair. E2F1 specifically has been shown to be a critical mediator of DNA repair; however, little is known about DNA repair...
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| Publicado no: | Sci Rep |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7578094/ https://ncbi.nlm.nih.gov/pubmed/33087787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74877-1 |
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