Ubiquitin–proteasome system involvement in Huntington’s disease

Por Ortega, Zaira, Lucas, Jose J.
Publicado em 2014

NFAT/Fas signaling mediates the neuronal apoptosis and motor side effects of GSK-3 inhibition in a mouse model of lithium therapy

Por Gómez-Sintes, Raquel, Lucas, José J.
Publicado em 2010

Neuronal Apoptosis and Motor Deficits in Mice with Genetic Inhibition of GSK-3 Are Fas-Dependent

Por Gómez-Sintes, Raquel, Lucas, José J.
Publicado em 2013

Targeting the proteasome in epilepsy

Por Engel, Tobias, Lucas, Jose J., Henshall, David C.
Publicado no Oncotarget (2017)

GSK-3 Mouse Models to Study Neuronal Apoptosis and Neurodegeneration

Por Gómez-Sintes, Raquel, Hernández, Félix, Lucas, José J., Avila, Jesús
Publicado em 2011

Mice with a naturally occurring DISC1 mutation display a broad spectrum of behaviors associated to psychiatric disorders

Por Gómez-Sintes, Raquel, Kvajo, Mirna, Gogos, Joseph A., Lucas, José J.
Publicado em 2014

Decreased nuclear β-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3β conditional transgenic mice

Por Lucas, José J., Hernández, Félix, Gómez-Ramos, Pilar, Morán, María A., Hen, René, Avila, Jesús
Publicado em 2001

Neuronal apoptosis and reversible motor deficit in dominant-negative GSK-3 conditional transgenic mice

Por Gómez-Sintes, Raquel, Hernández, Félix, Bortolozzi, Analía, Artigas, Francesc, Avila, Jesús, Zaratin, Paola, Gotteland, Jean Pierre, Lucas, José J
Publicado em 2007

In vivo inhibition of the mitochondrial H(+)-ATP synthase in neurons promotes metabolic preconditioning

Por Formentini, Laura, Pereira, Marta P, Sánchez-Cenizo, Laura, Santacatterina, Fulvio, Lucas, José J, Navarro, Carmen, Martínez-Serrano, Alberto, Cuezva, José M
Publicado em 2014

Striatal-Enriched Protein Tyrosine Phosphatase Expression and Activity in Huntington's Disease: A STEP in the Resistance to Excitotoxicity

Por Saavedra, Ana, Giralt, Albert, Rué, Laura, Xifró, Xavier, Xu, Jian, Ortega, Zaira, Lucas, José J., Lombroso, Paul J., Alberch, Jordi, Pérez-Navarro, Esther
Publicado em 2011

Prion-mediated neurodegeneration is associated with early impairment of the ubiquitin–proteasome system

Por McKinnon, Chris, Goold, Rob, Andre, Ralph, Devoy, Anny, Ortega, Zaira, Moonga, Julie, Linehan, Jacqueline M., Brandner, Sebastian, Lucas, José J., Collinge, John, Tabrizi, Sarah J.
Publicado no Acta Neuropathol (2015)

Accumulation of ubiquitin conjugates in a polyglutamine disease model occurs without global ubiquitin/proteasome system impairment

Por Maynard, Christa J., Böttcher, Claudia, Ortega, Zaira, Smith, Ruben, Florea, Bogdan I., Díaz-Hernández, Miguel, Brundin, Patrik, Overkleeft, Hermen S., Li, Jia-Yi, Lucas, Jose J., Dantuma, Nico P.
Publicado em 2009

Spatiotemporal progression of ubiquitin-proteasome system inhibition after status epilepticus suggests protective adaptation against hippocampal injury

Por Engel, Tobias, Martinez-Villarreal, Jaime, Henke, Christine, Jimenez-Mateos, Eva M., Sanz-Rodriguez, Amaya, Alves, Mariana, Hernandez-Santana, Yasmina, Brennan, Gary P., Kenny, Aidan, Campbell, Aoife, Lucas, Jose J., Henshall, David C.
Publicado no Mol Neurodegener (2017)