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Neuronal Apoptosis and Motor Deficits in Mice with Genetic Inhibition of GSK-3 Are Fas-Dependent

Glycogen synthase kinase-3 (GSK-3) inhibitors have been postulated as useful therapeutic tools for the treatment of chronic neurodegenerative and neuropsychiatric diseases. Nevertheless the clinical use of these inhibitors has been limited by their common side effects. Lithium, a non-selective GSK-3...

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Detalhes bibliográficos
Main Authors: Gómez-Sintes, Raquel, Lucas, José J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734180/
https://ncbi.nlm.nih.gov/pubmed/23940673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070952
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