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GSK-3 Mouse Models to Study Neuronal Apoptosis and Neurodegeneration
Increased GSK-3 activity is believed to contribute to the etiology of chronic disorders like Alzheimer’s disease (AD), schizophrenia, diabetes, and some types of cancer, thus supporting therapeutic potential of GSK-3 inhibitors. Numerous mouse models with modified GSK-3 have been generated in order...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Research Foundation
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3217194/ https://ncbi.nlm.nih.gov/pubmed/22110426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2011.00045 |
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