Selective Accumulation of Aggregation-Prone Proteasome Substrates in Response to Proteotoxic Stress

Por Salomons, Florian A., Menéndez-Benito, Victoria, Böttcher, Claudia, McCray, Brett A., Taylor, J. Paul, Dantuma, Nico P.
Publicado em 2009

Ataxin‐3 consolidates the MDC1‐dependent DNA double‐strand break response by counteracting the SUMO‐targeted ubiquitin ligase RNF4

Por Pfeiffer, Annika, Luijsterburg, Martijn S, Acs, Klara, Wiegant, Wouter W, Helfricht, Angela, Herzog, Laura K, Minoia, Melania, Böttcher, Claudia, Salomons, Florian A, van Attikum, Haico, Dantuma, Nico P
Publicado no EMBO J (2017)

Accumulation of ubiquitin conjugates in a polyglutamine disease model occurs without global ubiquitin/proteasome system impairment

Por Maynard, Christa J., Böttcher, Claudia, Ortega, Zaira, Smith, Ruben, Florea, Bogdan I., Díaz-Hernández, Miguel, Brundin, Patrik, Overkleeft, Hermen S., Li, Jia-Yi, Lucas, Jose J., Dantuma, Nico P.
Publicado em 2009

Alzheimer's disease-associated ubiquilin-1 regulates presenilin-1 accumulation and aggresome formation

Por Viswanathan, Jayashree, Haapasalo, Annakaisa, Böttcher, Claudia, Miettinen, Riitta, Kurkinen, Kaisa M.A., Lu, Alice, Thomas, Anne, Maynard, Christa J., Romano, Donna, Hyman, Bradley T., Berezovska, Oksana, Bertram, Lars, Soininen, Hilkka, Dantuma, Nico P., Tanzi, Rudolph E., Hiltunen, Mikko
Publicado em 2011