Striatal-Enriched Protein Tyrosine Phosphatase Expression and Activity in Huntington's Disease: A STEP in the Resistance to Excitotoxicity

Striatal-enriched protein tyrosine phosphatase (STEP) is highly expressed in striatal projection neurons, the neuronal population most affected in Huntington's disease. Here, we examined STEP expression and phosphorylation, which regulates its activity, in N-terminal exon-1 and full-length muta...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Saavedra, Ana, Giralt, Albert, Rué, Laura, Xifró, Xavier, Xu, Jian, Ortega, Zaira, Lucas, José J., Lombroso, Paul J., Alberch, Jordi, Pérez-Navarro, Esther
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2011
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472648/
https://ncbi.nlm.nih.gov/pubmed/21632937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3446-10.2011
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