Striatal-Enriched Protein Tyrosine Phosphatase Expression and Activity in Huntington's Disease: A STEP in the Resistance to Excitotoxicity

Striatal-enriched protein tyrosine phosphatase (STEP) is highly expressed in striatal projection neurons, the neuronal population most affected in Huntington's disease. Here, we examined STEP expression and phosphorylation, which regulates its activity, in N-terminal exon-1 and full-length muta...

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Detalhes bibliográficos
Main Authors: Saavedra, Ana, Giralt, Albert, Rué, Laura, Xifró, Xavier, Xu, Jian, Ortega, Zaira, Lucas, José J., Lombroso, Paul J., Alberch, Jordi, Pérez-Navarro, Esther
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472648/
https://ncbi.nlm.nih.gov/pubmed/21632937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3446-10.2011
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