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BDNF Induces Striatal-Enriched Protein Tyrosine Phosphatase 61 Degradation Through the Proteasome

Brain-derived neurotrophic factor (BDNF) promotes synaptic strengthening through the regulation of kinase and phosphatase activity. Conversely, striatal-enriched protein tyrosine phosphatase (STEP) opposes synaptic strengthening through inactivation or internalization of signaling molecules. Here, w...

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Detalhes bibliográficos
Publicado no:Mol Neurobiol
Main Authors: Saavedra, Ana, Puigdellívol, Mar, Tyebji, Shiraz, Kurup, Pradeep, Xu, Jian, Ginés, Silvia, Alberch, Jordi, Lombroso, Paul J., Pérez-Navarro, Esther
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4738169/
https://ncbi.nlm.nih.gov/pubmed/26223799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-015-9335-7
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