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Striatal-enriched protein tyrosine phosphatase modulates nociception: evidence from genetic deletion and pharmacological inhibition

The information from nociceptors is processed in the dorsal horn of the spinal cord by complex circuits involving excitatory and inhibitory interneurons. It is well documented that GluN2B and ERK1/2 phosphorylation contributes to central sensitization. Striatal-enriched protein tyrosine phosphatase...

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Detalhes bibliográficos
Publicado no:Pain
Main Authors: Azkona, Garikoitz, Saavedra, Ana, Aira, Zigor, Aluja, David, Xifró, Xavier, Baguley, Tyler, Alberch, Jordi, Ellman, Jonathan A., Lombroso, Paul J., Azkue, Jon J., Pérez-Navarro, Esther
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4809206/
https://ncbi.nlm.nih.gov/pubmed/26270590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000000329
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