Apoptosis, Bcl-2 family proteins and caspases: the ABCs of seizure-damage and epileptogenesis?

Por Engel, Tobias, Henshall, David C
Publicado em 2009

Contribution of apoptosis-associated signaling pathways to epileptogenesis: lessons from Bcl-2 family knockouts

Por Henshall, David C., Engel, Tobias
Publicado em 2013

The ATP-Gated P2X7 Receptor As a Target for the Treatment of Drug-Resistant Epilepsy

Por Beamer, Edward, Fischer, Wolfgang, Engel, Tobias
Publicado no Front Neurosci (2017)

The Metabotropic Purinergic P2Y Receptor Family as Novel Drug Target in Epilepsy

Por Alves, Mariana, Beamer, Edward, Engel, Tobias
Publicado no Front Pharmacol (2018)

Differential Expression of the Metabotropic P2Y Receptor Family in the Cortex Following Status Epilepticus and Neuroprotection via P2Y(1) Antagonism in Mice

Por Alves, Mariana, Smith, Jonathon, Engel, Tobias
Publicado no Front Pharmacol (2020)

Targeting the proteasome in epilepsy

Por Engel, Tobias, Lucas, Jose J., Henshall, David C.
Publicado no Oncotarget (2017)

Full Reversal of Alzheimer's Disease-Like Phenotype in a Mouse Model with Conditional Overexpression of Glycogen Synthase Kinase-3

Por Engel, Tobias, Hernández, Félix, Avila, Jesús, Lucas, José J.
Publicado no J Neurosci (2006)

Elevated p53 and lower MDM2 expression in hippocampus from patients with intractable temporal lobe epilepsy

Por Engel, Tobias, Murphy, Brona M., Schindler, Clara K., Henshall, David C.
Publicado em 2007

In vivo contributions of BH3-only proteins to neuronal death following seizures, ischemia, and traumatic brain injury

Por Engel, Tobias, Plesnila, Nikolaus, Prehn, Jochen H M, Henshall, David C
Publicado em 2011

P2X receptors as targets for the treatment of status epilepticus

Por Henshall, David C., Diaz-Hernandez, Miguel, Miras-Portugal, M. Teresa, Engel, Tobias
Publicado em 2013

Tau Phosphorylation in a Mouse Model of Temporal Lobe Epilepsy

Por Alves, Marianna, Kenny, Aidan, de Leo, Gioacchino, Beamer, Edward H., Engel, Tobias
Publicado no Front Aging Neurosci (2019)

Deletion of puma protects hippocampal neurons in a model of severe status epilepticus

Por Engel, Tobias, Hatazaki, Seiji, Tanaka, Katsuhiro, Prehn, Jochen H.M., Henshall, David C.
Publicado em 2010

P2X7 receptor in epilepsy; role in pathophysiology and potential targeting for seizure control

Por Engel, Tobias, Jimenez-Pacheco, Alba, Miras-Portugal, Maria Teresa, Diaz-Hernandez, Miguel, Henshall, David C
Publicado em 2012

Haploinsufficient TNAP Mice Display Decreased Extracellular ATP Levels and Expression of Pannexin-1 Channels

Por Sebastián-Serrano, Álvaro, de Diego-García, Laura, Henshall, David C., Engel, Tobías, Díaz-Hernández, Miguel
Publicado no Front Pharmacol (2018)

De-repression of myelin-regulating gene expression after status epilepticus in mice lacking the C/EBP homologous protein CHOP

Por Sheedy, Caroline, Mooney, Claire, Jimenez-Mateos, Eva, Sanz-Rodriguez, Amaya, Langa, Elena, Mooney, Catherine, Engel, Tobias
Publicado no Int J Physiol Pathophysiol Pharmacol (2014)

Tubby-like protein 1 (Tulp1) is a target of microRNA-134 and is down-regulated in experimental epilepsy

Por Rodriguez, Amaya Sanz, Engel, Tobias, Palfi, Arpad, Farrar, G Jane, Henshall, David C, Jimenez-Mateos, Eva M
Publicado no Int J Physiol Pathophysiol Pharmacol (2017)

Transgenic Overexpression of 14-3-3 Zeta Protects Hippocampus against Endoplasmic Reticulum Stress and Status Epilepticus In Vivo

Por Brennan, Gary P., Jimenez-Mateos, Eva M., McKiernan, Ross C., Engel, Tobias, Tzivion, Guri, Henshall, David C.
Publicado em 2013

Bok Is Not Pro-Apoptotic But Suppresses Poly ADP-Ribose Polymerase-Dependent Cell Death Pathways and Protects against Excitotoxic and Seizure-Induced Neuronal Injury

Por D'Orsi, Beatrice, Engel, Tobias, Pfeiffer, Shona, Nandi, Saheli, Kaufmann, Thomas, Henshall, David C., Prehn, Jochen H. M.
Publicado no J Neurosci (2016)

Expression of neurogenesis genes in human temporal lobe epilepsy with hippocampal sclerosis

Por Engel, Tobias, Schindler, Clara K, Sanz-Rodriguez, Amaya, Conroy, Ronan M, Meller, Robert, Simon, Roger P, Henshall, David C
Publicado em 2010

Evaluation of a New Culture Protocol for Enhancing Fungal Detection Rates in Respiratory Samples of Cystic Fibrosis Patients

Por Engel, Tobias G.P., Tehupeiory-Kooreman, Marlou, Melchers, Willem J.G., Reijers, Monique H., Merkus, Peter, Verweij, Paul E.
Publicado no J Fungi (Basel) (2020)