Bok Is Not Pro-Apoptotic But Suppresses Poly ADP-Ribose Polymerase-Dependent Cell Death Pathways and Protects against Excitotoxic and Seizure-Induced Neuronal Injury

Bok (Bcl-2-related ovarian killer) is a Bcl-2 family member that, because of its predicted structural homology to Bax and Bak, has been proposed to be a pro-apoptotic protein. In this study, we demonstrate that Bok is highly expressed in neurons of the mouse brain but that bok was not required for s...

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Publicat a:J Neurosci
Autors principals: D'Orsi, Beatrice, Engel, Tobias, Pfeiffer, Shona, Nandi, Saheli, Kaufmann, Thomas, Henshall, David C., Prehn, Jochen H. M.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2016
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601822/
https://ncbi.nlm.nih.gov/pubmed/27098698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3780-15.2016
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