FLIP(L): the pseudo‐caspase

nork Smyth, Peter, Sessler, Tamas, Scott, Christopher J., Longley, Daniel B.
Argitaratua izan da FEBS J (2020)

Therapeutics Targeting the Core Apoptotic Machinery

nork Hamilton, Claudia, Fox, Jennifer P., Longley, Daniel B., Higgins, Catherine A.
Argitaratua izan da Cancers (Basel) (2021)

Voltage dependent anion channel-1 regulates death receptor mediated apoptosis by enabling cleavage of caspase-8

nork Chacko, Alex D, Liberante, Fabio, Paul, Ian, Longley, Daniel B, Fennell, Dean A
Argitaratua 2010

Epithelial‐to‐mesenchymal transition signature assessment in colorectal cancer quantifies tumour stromal content rather than true transition

nork McCorry, Amy MB, Loughrey, Maurice B, Longley, Daniel B, Lawler, Mark, Dunne, Philip D
Argitaratua izan da J Pathol (2018)

Chemotherapy-induced activation of ADAM-17: a novel mechanism of drug resistance in colorectal cancer

nork Kyula, Joan N., Van Schaeybroeck, Sandra, Doherty, Joanne, Fenning, Catherine S., Longley, Daniel B., Johnston, Patrick G.
Argitaratua 2010

Constitutive and Treatment-Induced CXCL8-Signalling Selectively Modulates the Efficacy of Anti-Metabolite Therapeutics in Metastatic Prostate Cancer

nork Wilson, Catherine, Maxwell, Pamela J., Longley, Daniel B., Wilson, Richard H., Johnston, Patrick G., Waugh, David J. J.
Argitaratua 2012

Src and ADAM-17-Mediated Shedding of Transforming Growth Factor-α Is a Mechanism of Acute Resistance to TRAIL

nork Van Schaeybroeck, Sandra, Kelly, Donal M., Kyula, Joan, Stokesberry, Susan, Fennell, Dean A., Johnston, Patrick G., Longley, Daniel B.
Argitaratua 2008

Heterogeneous responses to low level death receptor activation are explained by random molecular assembly of the Caspase-8 activation platform

nork Matveeva, Anna, Fichtner, Michael, McAllister, Katherine, McCann, Christopher, Sturrock, Marc, Longley, Daniel B., Prehn, Jochen H. M.
Argitaratua izan da PLoS Comput Biol (2019)

Oncogenic Kras promotes chemotherapy-induced growth factor shedding via ADAM17

nork Van Schaeybroeck, Sandra, Kyula, Joan N., Fenton, Audrey, Fenning, Catherine S., Sasazuki, Takehiko, Shirasawa, Senji, Longley, Daniel B., Johnston, Patrick G.
Argitaratua 2010

Calbindin 2 (CALB2) Regulates 5-Fluorouracil Sensitivity in Colorectal Cancer by Modulating the Intrinsic Apoptotic Pathway

nork Stevenson, Leanne, Allen, Wendy L., Proutski, Irina, Stewart, Gail, Johnston, Louise, McCloskey, Karen, Wilson, Peter M., Longley, Daniel B., Johnston, Patrick G.
Argitaratua 2011

The Colorectal cancer disease-specific transcriptome may facilitate the discovery of more biologically and clinically relevant information

nork Allen, Wendy L, Jithesh, Puthen V, Oliver, Gavin R, Proutski, Irina, Longley, Daniel B, Lenz, Heinz-Josef, Proutski, Vitali, Harkin, Paul, Johnston, Patrick G
Argitaratua 2010

HDAC inhibition overcomes acute resistance to MEK inhibition in BRAF mutant colorectal cancer by down-regulation of c-FLIP(L)

nork Carson, Robbie, Celtikci, Basak, Fenning, Cathy, Javadi, Arman, Crawford, Nyree, Carbonell, Lucia Perez, Lawler, Mark, Longley, Daniel B., Johnston, Patrick G., Van Schaeybroeck, Sandra
Argitaratua izan da Clin Cancer Res (2015)

Simulating and predicting cellular and in vivo responses of colon cancer to combined treatment with chemotherapy and IAP antagonist Birinapant/TL32711

nork Crawford, Nyree, Salvucci, Manuela, Hellwig, Christian T, Lincoln, Frank A, Mooney, Ruth E, O’Connor, Carla L, Prehn, Jochen HM, Longley, Daniel B, Rehm, Markus
Argitaratua izan da Cell Death Differ (2018)

ELEVATION OF C-FLIP IN CASTRATE-RESISTANT PROSTATE CANCER ANTAGONIZES THERAPEUTIC RESPONSE TO ANDROGEN-RECEPTOR TARGETED THERAPY

nork McCourt, Clare, Maxwell, Pamela, Mazzucchelli, Roberta, Montironi, Rodolfo, Scarpelli, Marina, Salto-Tellez, Manuel, O’Sullivan, Joe M., Longley, Daniel B., Waugh, David J.J.
Argitaratua 2012

Vorinostat Eliminates Multicellular Resistance of Mesothelioma 3D Spheroids via Restoration of Noxa Expression

nork Barbone, Dario, Cheung, Priscilla, Battula, Sailaja, Busacca, Sara, Gray, Steven G., Longley, Daniel B., Bueno, Raphael, Sugarbaker, David J., Fennell, Dean A., Broaddus, V. Courtney
Argitaratua 2012

Identification of galanin and its receptor GalR1 as novel determinants of resistance to chemotherapy and potential biomarkers in colorectal cancer

nork Stevenson, Leanne, Allen, Wendy L, Turkington, Richard, Jithesh, Puthen V, Proutski, Irina, Stewart, Gail, Lenz, Heinz-Josef, Schaeybroeck, Sandra Van, Longley, Daniel B, Johnston, Patrick G
Argitaratua 2012

Pharmacogenomic profiling and pathway analyses identify MAPK-dependent migration as an acute response to SN38 in p53 null and mutant colorectal cancer cells

nork Allen, Wendy L., Turkington, Richard C., Stevenson, Leanne, Carson, Gail, Coyle, Vicky M., Hector, Suzanne, Dunne, Philip, Van Schaeybroeck, Sandra, Longley, Daniel B., Johnston, Patrick G.
Argitaratua 2012

Efficient Drug Delivery and Induction of Apoptosis in Colorectal Tumors Using a Death Receptor 5-Targeted Nanomedicine

nork Schmid, Daniela, Fay, Francois, Small, Donna M, Jaworski, Jakub, Riley, Joel S, Tegazzini, Diana, Fenning, Cathy, Jones, David S, Johnston, Patrick G, Longley, Daniel B, Scott, Christopher J
Argitaratua izan da Mol Ther (2014)

Stratified analysis reveals chemokine-like factor (CKLF) as a potential prognostic marker in the MSI-immune consensus molecular subtype CMS1 of colorectal cancer

nork Dunne, Philip D., O'Reilly, Paul G., Coleman, Helen G., Gray, Ronan T., Longley, Daniel B., Johnston, Patrick G., Salto-Tellez, Manuel, Lawler, Mark, McArt, Darragh G.
Argitaratua izan da Oncotarget (2016)

Development of an advanced nanoformulation for the intracellular delivery of a caspase-3 selective activity-based probe

nork Cogo, Francesco, Poreba, Marcin, Rut, Wioletta, Groborz, Katarzyna, Smyth, Peter, Johnston, Michael C., Williams, Richard, Longley, Daniel B., Burden, Roberta E., Salvesen, Guy S., Drag, Marcin, Scott, Christopher J.
Argitaratua izan da Nanoscale (2019)