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Constitutive and Treatment-Induced CXCL8-Signalling Selectively Modulates the Efficacy of Anti-Metabolite Therapeutics in Metastatic Prostate Cancer

BACKGROUND: The current study was undertaken to characterize the effect of anti-metabolites on inducing CXCL8 signaling and determining whether the constitutive and/or drug-induced CXCL8 signaling in metastatic prostate cancer (CaP) cells modulates their sensitivity to this class of agent. METHODS:...

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Detalhes bibliográficos
Main Authors: Wilson, Catherine, Maxwell, Pamela J., Longley, Daniel B., Wilson, Richard H., Johnston, Patrick G., Waugh, David J. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348872/
https://ncbi.nlm.nih.gov/pubmed/22590561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036545
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