Potentiation of Inflammatory CXCL8 Signalling Sustains Cell Survival in PTEN-deficient Prostate Carcinoma

BACKGROUND: Inflammation and genetic instability are enabling characteristics of prostate carcinoma (PCa). Inactivation of the tumour suppressor gene phosphatase and tensin homolog (PTEN) is prevalent in early PCa. The relationship of PTEN deficiency to inflammatory signalling remains to be characte...

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Detalhes bibliográficos
Main Authors: Maxwell, Pamela J., Coulter, Jonathan, Walker, Steven M., McKechnie, Melanie, Neisen, Jessica, McCabe, Nuala, Kennedy, Richard D., Salto-Tellez, Manuel, Albanese, Chris, Waugh, David J.J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185293/
https://ncbi.nlm.nih.gov/pubmed/22939387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eururo.2012.08.032
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