Identification of Clinically Relevant Molecular Subtypes in Colorectal Cancer: The Dawning of a New Era

Por Johnston, Patrick G.
Publicado em 2014

Expert Opinion: Future Frontiers and Challenges in Cancer Medicine

Por Johnston, Patrick G., Lawler, Mark
Publicado em 2012

Personalized Medicine: Does the Molecular Suit Fit?

Por Liu, Edison T., Johnston, Patrick G.
Publicado em 2013

The High Tide of Cancer Research in Europe

Por Johnston, Patrick G., Pinedo, H.M.
Publicado em 2011

European Perspectives: A Dialogue with the European Oncology Community

Por Le Chevalier, Thierry, Conte, Pierfranco, Johnston, Patrick G., Pinedo, H.M.
Publicado em 2012

Identification of genes differentially expressed between benign and osteopontin transformed rat mammary epithelial cells

Por Kurisetty, Vittal V, Johnston, Patrick G, Rudland, Philip S, El-Tanani, Mohamed K
Publicado em 2009

Dynamical Systems Analysis of Mitochondrial BAK Activation Kinetics Predicts Resistance to BH3 Domains

Por Grills, Claire, Crawford, Nyree, Chacko, Alex, Johnston, Patrick G., O'Rourke, Francesca, Fennell, Dean A.
Publicado em 2008

Chemotherapy-induced activation of ADAM-17: a novel mechanism of drug resistance in colorectal cancer

Por Kyula, Joan N., Van Schaeybroeck, Sandra, Doherty, Joanne, Fenning, Catherine S., Longley, Daniel B., Johnston, Patrick G.
Publicado em 2010

Constitutive and Treatment-Induced CXCL8-Signalling Selectively Modulates the Efficacy of Anti-Metabolite Therapeutics in Metastatic Prostate Cancer

Por Wilson, Catherine, Maxwell, Pamela J., Longley, Daniel B., Wilson, Richard H., Johnston, Patrick G., Waugh, David J. J.
Publicado em 2012

Src and ADAM-17-Mediated Shedding of Transforming Growth Factor-α Is a Mechanism of Acute Resistance to TRAIL

Por Van Schaeybroeck, Sandra, Kelly, Donal M., Kyula, Joan, Stokesberry, Susan, Fennell, Dean A., Johnston, Patrick G., Longley, Daniel B.
Publicado em 2008

Oncogenic Kras promotes chemotherapy-induced growth factor shedding via ADAM17

Por Van Schaeybroeck, Sandra, Kyula, Joan N., Fenton, Audrey, Fenning, Catherine S., Sasazuki, Takehiko, Shirasawa, Senji, Longley, Daniel B., Johnston, Patrick G.
Publicado em 2010

The Clinical Significance of Cathepsin S Expression in Human Astrocytomas

Por Flannery, Thomas, Gibson, David, Mirakhur, Menakshi, McQuaid, Stephen, Greenan, Caroline, Trimble, Anne, Walker, Brian, McCormick, Derek, Johnston, Patrick G.
Publicado em 2003

Calbindin 2 (CALB2) Regulates 5-Fluorouracil Sensitivity in Colorectal Cancer by Modulating the Intrinsic Apoptotic Pathway

Por Stevenson, Leanne, Allen, Wendy L., Proutski, Irina, Stewart, Gail, Johnston, Louise, McCloskey, Karen, Wilson, Peter M., Longley, Daniel B., Johnston, Patrick G.
Publicado em 2011

The Colorectal cancer disease-specific transcriptome may facilitate the discovery of more biologically and clinically relevant information

Por Allen, Wendy L, Jithesh, Puthen V, Oliver, Gavin R, Proutski, Irina, Longley, Daniel B, Lenz, Heinz-Josef, Proutski, Vitali, Harkin, Paul, Johnston, Patrick G
Publicado em 2010

HDAC inhibition overcomes acute resistance to MEK inhibition in BRAF mutant colorectal cancer by down-regulation of c-FLIP(L)

Por Carson, Robbie, Celtikci, Basak, Fenning, Cathy, Javadi, Arman, Crawford, Nyree, Carbonell, Lucia Perez, Lawler, Mark, Longley, Daniel B., Johnston, Patrick G., Van Schaeybroeck, Sandra
Publicado no Clin Cancer Res (2015)

Identification of galanin and its receptor GalR1 as novel determinants of resistance to chemotherapy and potential biomarkers in colorectal cancer

Por Stevenson, Leanne, Allen, Wendy L, Turkington, Richard, Jithesh, Puthen V, Proutski, Irina, Stewart, Gail, Lenz, Heinz-Josef, Schaeybroeck, Sandra Van, Longley, Daniel B, Johnston, Patrick G
Publicado em 2012

Pharmacogenomic profiling and pathway analyses identify MAPK-dependent migration as an acute response to SN38 in p53 null and mutant colorectal cancer cells

Por Allen, Wendy L., Turkington, Richard C., Stevenson, Leanne, Carson, Gail, Coyle, Vicky M., Hector, Suzanne, Dunne, Philip, Van Schaeybroeck, Sandra, Longley, Daniel B., Johnston, Patrick G.
Publicado em 2012

Efficient Drug Delivery and Induction of Apoptosis in Colorectal Tumors Using a Death Receptor 5-Targeted Nanomedicine

Por Schmid, Daniela, Fay, Francois, Small, Donna M, Jaworski, Jakub, Riley, Joel S, Tegazzini, Diana, Fenning, Cathy, Jones, David S, Johnston, Patrick G, Longley, Daniel B, Scott, Christopher J
Publicado no Mol Ther (2014)

Stratified analysis reveals chemokine-like factor (CKLF) as a potential prognostic marker in the MSI-immune consensus molecular subtype CMS1 of colorectal cancer

Por Dunne, Philip D., O'Reilly, Paul G., Coleman, Helen G., Gray, Ronan T., Longley, Daniel B., Johnston, Patrick G., Salto-Tellez, Manuel, Lawler, Mark, McArt, Darragh G.
Publicado no Oncotarget (2016)

A Predictive Genetic Signature for Response to Fluoropyrimidine-Based Neoadjuvant Chemoradiation in Clinical Stage II and III Rectal Cancer

Por Chan, Jason, Kinsella, Michael T., Willis, Joseph E., Hu, Huankai, Reynolds, Harry, Delaney, Conor, McCulla, Andrea, Deharo, Steve, Ahdesmäki, Miika, Allen, Wendy Louise, Johnston, Patrick G., Kinsella, Timothy J.
Publicado em 2013