Calbindin 2 (CALB2) Regulates 5-Fluorouracil Sensitivity in Colorectal Cancer by Modulating the Intrinsic Apoptotic Pathway

by Stevenson, Leanne, Allen, Wendy L., Proutski, Irina, Stewart, Gail, Johnston, Louise, McCloskey, Karen, Wilson, Peter M., Longley, Daniel B., Johnston, Patrick G.
Published 2011

The Colorectal cancer disease-specific transcriptome may facilitate the discovery of more biologically and clinically relevant information

by Allen, Wendy L, Jithesh, Puthen V, Oliver, Gavin R, Proutski, Irina, Longley, Daniel B, Lenz, Heinz-Josef, Proutski, Vitali, Harkin, Paul, Johnston, Patrick G
Published 2010

Identification of galanin and its receptor GalR1 as novel determinants of resistance to chemotherapy and potential biomarkers in colorectal cancer

by Stevenson, Leanne, Allen, Wendy L, Turkington, Richard, Jithesh, Puthen V, Proutski, Irina, Stewart, Gail, Lenz, Heinz-Josef, Schaeybroeck, Sandra Van, Longley, Daniel B, Johnston, Patrick G
Published 2012

Pharmacogenomic profiling and pathway analyses identify MAPK-dependent migration as an acute response to SN38 in p53 null and mutant colorectal cancer cells

by Allen, Wendy L., Turkington, Richard C., Stevenson, Leanne, Carson, Gail, Coyle, Vicky M., Hector, Suzanne, Dunne, Philip, Van Schaeybroeck, Sandra, Longley, Daniel B., Johnston, Patrick G.
Published 2012

A systems biology approach identifies SART1 as a novel determinant of both 5-fluorouracil and SN38 drug resistance in colorectal cancer

by Allen, Wendy L., Stevenson, Leanne, Coyle, Vicky M., Jithesh, Puthen V., Proutski, Irina, Carson, Gail, Gordon, Michael A, Lenz, Heinz-Josef D, Van Schaeybroeck, Sandra, Longley, Daniel B., Johnston, Patrick G.
Published 2011

The unfolded protein response: a novel therapeutic target for poor prognostic BRAF mutant colorectal cancer

by Forsythe, Nicholas, Refaat, Alaa, Javadi, Arman, Khawaja, Hajrah, Weir, Jessica-Anne, Emam, Heba, Allen, Wendy L., Burkamp, Frank, Popovici, Vlad, Jithesh, Puthen V., Isella, Claudio, Labonte, Melissa J., Mills, Ian G., Johnston, Patrick G., Van Schaeybroeck, Sandra
Published in Mol Cancer Ther (2018)

RALB GTPase: a critical regulator of DR5 expression and TRAIL sensitivity in KRAS mutant colorectal cancer

by Khawaja, Hajrah, Campbell, Andrew, Roberts, Jamie Z., Javadi, Arman, O’Reilly, Paul, McArt, Darragh, Allen, Wendy L., Majkut, Joanna, Rehm, Markus, Bardelli, Alberto, Di Nicolantonio, Federica, Scott, Christopher J., Kennedy, Richard, Vitale, Nicolas, Harrison, Timothy, Sansom, Owen J., Longley, Daniel B., Evergren, Emma, Van Schaeybroeck, Sandra
Published in Cell Death Dis (2020)

The pseudo-caspase FLIP(L) regulates cell fate following p53 activation

by Lees, Andrea, McIntyre, Alexander J., Crawford, Nyree T., Falcone, Fiammetta, McCann, Christopher, Holohan, Caitriona, Quinn, Gerard P., Roberts, Jamie Z., Sessler, Tamas, Gallagher, Peter F., Gregg, Gemma M. A., McAllister, Katherine, McLaughlin, Kirsty M., Allen, Wendy L., Egan, Laurence J., Ryan, Aideen E., Labonte-Wilson, Melissa J., Dunne, Philip D., Wappett, Mark, Coyle, Vicky M., Johnston, Patrick G., Kerr, Emma M., Longley, Daniel B., McDade, Simon S.
Published in Proc Natl Acad Sci U S A (2020)

Transcriptional Subtyping and CD8 Immunohistochemistry Identifies Patients With Stage II and III Colorectal Cancer With Poor Prognosis Who Benefit From Adjuvant Chemotherapy

by Allen, Wendy L., Dunne, Philip D., McDade, Simon, Scanlon, Enya, Loughrey, Maurice, Coleman, Helen G., McCann, Christopher, McLaughlin, Kristy, Nemeth, Zsuzsanna, Syed, Najeeb Ashraf, Jithesh, Puthen Veettil, Arthur, Ken, Wilson, Richard, Coyle, Vicky M., McArt, Darragh, Murray, Graeme I., Samuel, Leslie, Nuciforo, Paolo, Jimenez, Jose, Argiles, Guillem, Dienstmann, Rodrigo, Tabernero, Josef, Picariello, Lucia, Messerini, Luca, Nobili, Stefania, Mini, Enrico, Sheahan, Kieran, Ryan, Elizabeth, Johnston, Patrick G., Van Schaeybroeck, Sandra, Lawler, Mark, Longley, Daniel B.
Published in JCO Precis Oncol (2018)