Dynamical Systems Analysis of Mitochondrial BAK Activation Kinetics Predicts Resistance to BH3 Domains

Por Grills, Claire, Crawford, Nyree, Chacko, Alex, Johnston, Patrick G., O'Rourke, Francesca, Fennell, Dean A.
Publicado em 2008

HDAC inhibition overcomes acute resistance to MEK inhibition in BRAF mutant colorectal cancer by down-regulation of c-FLIP(L)

Por Carson, Robbie, Celtikci, Basak, Fenning, Cathy, Javadi, Arman, Crawford, Nyree, Carbonell, Lucia Perez, Lawler, Mark, Longley, Daniel B., Johnston, Patrick G., Van Schaeybroeck, Sandra
Publicado no Clin Cancer Res (2015)

BRCA1 is a key regulator of breast differentiation through activation of Notch signalling with implications for anti-endocrine treatment of breast cancers

Por Buckley, Niamh E., Nic An tSaoir, Caoimhe B., Blayney, Jaine K., Oram, Lisa C., Crawford, Nyree T., D’Costa, Zenobia C., Quinn, Jennifer E., Kennedy, Richard D., Harkin, D. Paul, Mullan, Paul B.
Publicado em 2013

PTEN deficiency promotes macrophage infiltration and hypersensitivity of prostate cancer to IAP antagonist/radiation combination therapy

Por Armstrong, Chris W.D., Maxwell, Pamela J., Ong, Chee Wee, Redmond, Kelly M., McCann, Christopher, Neisen, Jessica, Ward, George A., Chessari, Gianni, Johnson, Christopher, Crawford, Nyree T., LaBonte, Melissa J., Prise, Kevin M., Robson, Tracy, Salto-Tellez, Manuel, Longley, Daniel B., Waugh, David J.J.
Publicado no Oncotarget (2016)

TBX2 represses CST6 resulting in uncontrolled legumain activity to sustain breast cancer proliferation: a novel cancer-selective target pathway with therapeutic opportunities.

Por D'Costa, Zenobia C., Higgins, Catherine, Ong, Chee Wee, Irwin, Gareth W., Boyle, David, McArt, Darragh G., McCloskey, Karen, Buckley, Niamh E., Crawford, Nyree T., Thiagarajan, Lalitha, Murray, James T., Kennedy, Richard D., Mulligan, Karl A., Harkin, D. Paul, Waugh, David J.J., Scott, Chris J., Salto-Tellez, Manuel, Williams, Richard, Mullan, Paul B.
Publicado em 2014