Efficient Drug Delivery and Induction of Apoptosis in Colorectal Tumors Using a Death Receptor 5-Targeted Nanomedicine

Death Receptor 5 (DR5) is a pro-apoptotic cell-surface receptor that is a potential therapeutic target in cancer. Despite the potency of DR5-targeting agents in preclinical models, the translation of these effects into the clinic remains disappointing. Herein, we report an alternative approach to ex...

詳細記述

保存先:
書誌詳細
出版年:Mol Ther
主要な著者: Schmid, Daniela, Fay, Francois, Small, Donna M, Jaworski, Jakub, Riley, Joel S, Tegazzini, Diana, Fenning, Cathy, Jones, David S, Johnston, Patrick G, Longley, Daniel B, Scott, Christopher J
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2014
主題:
Original Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4429693/
https://ncbi.nlm.nih.gov/pubmed/25200008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.137
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