Rationale and Means to Target Pro-Inflammatory Interleukin-8 (CXCL8) Signaling in Cancer

por Campbell, Laura M., Maxwell, Pamela J., Waugh, David J.J.
Publicado 2013

Tumor-derived CXCL8 signaling augments stroma-derived CCL2-promoted proliferation and CXCL12-mediated invasion of PTEN-deficient prostate cancer cells

por Maxwell, Pamela J., Neisen, Jessica, Messenger, Johanna, Waugh, David J.J.
Publicado 2014

CD44-mediated activation of α5β1-integrin, cortactin and paxillin signaling underpins adhesion of basal-like breast cancer cells to endothelium and Fibronectin-enriched matrices

por McFarlane, Suzanne, McFarlane, Cheryl, Montgomery, Nicola, Hill, Ashleigh, Waugh, David J.J.
Publicado en Oncotarget (2015)

Constitutive and Treatment-Induced CXCL8-Signalling Selectively Modulates the Efficacy of Anti-Metabolite Therapeutics in Metastatic Prostate Cancer

por Wilson, Catherine, Maxwell, Pamela J., Longley, Daniel B., Wilson, Richard H., Johnston, Patrick G., Waugh, David J. J.
Publicado 2012

ATM Kinase Inhibition Preferentially Sensitises PTEN-Deficient Prostate Tumour Cells to Ionising Radiation

por Hanna, Conor, Dunne, Victoria L., Walker, Steven M., Butterworth, Karl T., McCabe, Nuala, Waugh, David J. J., Kennedy, Richard D., Prise, Kevin M.
Publicado en Cancers (Basel) (2020)

ELEVATION OF C-FLIP IN CASTRATE-RESISTANT PROSTATE CANCER ANTAGONIZES THERAPEUTIC RESPONSE TO ANDROGEN-RECEPTOR TARGETED THERAPY

por McCourt, Clare, Maxwell, Pamela, Mazzucchelli, Roberta, Montironi, Rodolfo, Scarpelli, Marina, Salto-Tellez, Manuel, O’Sullivan, Joe M., Longley, Daniel B., Waugh, David J.J.
Publicado 2012

Potentiation of Inflammatory CXCL8 Signalling Sustains Cell Survival in PTEN-deficient Prostate Carcinoma

por Maxwell, Pamela J., Coulter, Jonathan, Walker, Steven M., McKechnie, Melanie, Neisen, Jessica, McCabe, Nuala, Kennedy, Richard D., Salto-Tellez, Manuel, Albanese, Chris, Waugh, David J.J.
Publicado 2012

CD44 increases the efficiency of distant metastasis of breast cancer

por McFarlane, Suzanne, Coulter, Jonathan A., Tibbits, Paul, O'Grady, Anthony, McFarlane, Cheryl, Montgomery, Nicola, Hill, Ashleigh, McCarthy, Helen O., Young, Leonie S., Kay, Elaine W., Isacke, Clare M., Waugh, David J.J.
Publicado en Oncotarget (2015)

The prognostic value of the stem-like group in colorectal cancer using a panel of immunohistochemistry markers

por Ong, Chee Wee, Chong, Pei Yi, McArt, Darragh G., Chan, Jason Yongsheng, Tan, Hwee Tong, Kumar, Alan Prem, Chung, Maxey C. M., Clément, Marie-Véronique, Soong, Richie, Van Schaeybroeck, Sandra, Waugh, David J. J., Johnston, Patrick G., Dunne, Philip D., Salto-Tellez, Manuel
Publicado en Oncotarget (2015)

PTEN deficiency promotes macrophage infiltration and hypersensitivity of prostate cancer to IAP antagonist/radiation combination therapy

por Armstrong, Chris W.D., Maxwell, Pamela J., Ong, Chee Wee, Redmond, Kelly M., McCann, Christopher, Neisen, Jessica, Ward, George A., Chessari, Gianni, Johnson, Christopher, Crawford, Nyree T., LaBonte, Melissa J., Prise, Kevin M., Robson, Tracy, Salto-Tellez, Manuel, Longley, Daniel B., Waugh, David J.J.
Publicado en Oncotarget (2016)

Clinical and functional characterization of CXCR1/CXCR2 biology in the relapse and radiotherapy resistance of primary PTEN-deficient prostate carcinoma

por Armstrong, Chris W D, Coulter, Jonathan A, Ong, Chee Wee, Maxwell, Pamela J, Walker, Steven, Butterworth, Karl T, Lyubomska, Oksana, Berlingeri, Silvia, Gallagher, Rebecca, O’Sullivan, Joe M, Jain, Suneil, Mills, Ian G, Prise, Kevin M, Bristow, Robert G, LaBonte, Melissa J, Waugh, David J J
Publicado en NAR Cancer (2020)

TBX2 represses CST6 resulting in uncontrolled legumain activity to sustain breast cancer proliferation: a novel cancer-selective target pathway with therapeutic opportunities.

por D'Costa, Zenobia C., Higgins, Catherine, Ong, Chee Wee, Irwin, Gareth W., Boyle, David, McArt, Darragh G., McCloskey, Karen, Buckley, Niamh E., Crawford, Nyree T., Thiagarajan, Lalitha, Murray, James T., Kennedy, Richard D., Mulligan, Karl A., Harkin, D. Paul, Waugh, David J.J., Scott, Chris J., Salto-Tellez, Manuel, Williams, Richard, Mullan, Paul B.
Publicado 2014