Simulating and predicting cellular and in vivo responses of colon cancer to combined treatment with chemotherapy and IAP antagonist Birinapant/TL32711

Apoptosis resistance contributes to treatment failure in colorectal cancer (CRC). New treatments that reinstate apoptosis competency have potential to improve patient outcome but require predictive biomarkers to target them to responsive patient populations. Inhibitor of apoptosis proteins (IAPs) su...

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Bibliografiske detaljer
Udgivet i:Cell Death Differ
Main Authors: Crawford, Nyree, Salvucci, Manuela, Hellwig, Christian T, Lincoln, Frank A, Mooney, Ruth E, O’Connor, Carla L, Prehn, Jochen HM, Longley, Daniel B, Rehm, Markus
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989936/
https://ncbi.nlm.nih.gov/pubmed/29500433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0082-y
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