Effect of a Smac Mimetic (TL32711, Birinapant) on the Apoptotic Program and Apoptosis Biomarkers Examined with Validated Multiplex Immunoassays Fit for Clinical Use

PURPOSE: To support clinical pharmacodynamic evaluation of the Smac mimetic TL32711 (birinapant) and other apoptosis-targeting drugs, we describe the development, validation, and application of novel immunoassays for 15 cytosolic and membrane-associated proteins indicative of the induction, onset, a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Srivastava, Apurva K., Jaganathan, Soumya, Stephen, Laurie, Hollingshead, Melinda G., Layhee, Adam, Damour, Eric, Govindharajulu, Jeevan Prasaad, Donohue, Jennifer, Esposito, Dominic, Mapes, James P., Kinders, Robert J., Takebe, Naoko, Tomaszewski, Joseph E., Kummar, Shivaani, Doroshow, James H., Parchment, Ralph E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755826/
https://ncbi.nlm.nih.gov/pubmed/26446940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-3156
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados