Molecular subtype-specific responses of colon cancer cells to the SMAC mimetic Birinapant

Colorectal cancer is a molecularly heterogeneous disease. Responses to genotoxic chemotherapy in the adjuvant or palliative setting vary greatly between patients, and colorectal cancer cells often resist chemotherapy by evading apoptosis. Antagonists of an inhibitor of apoptosis proteins (IAPs) can...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Fichtner, Michael, Bozkurt, Emir, Salvucci, Manuela, McCann, Christopher, McAllister, Katherine A., Halang, Luise, Düssmann, Heiko, Kinsella, Sinéad, Crawford, Nyree, Sessler, Tamas, Longley, Daniel B., Prehn, Jochen H. M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7705699/
https://ncbi.nlm.nih.gov/pubmed/33257690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03232-z
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