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Combination effects of SMAC mimetic birinapant with TNFα, TRAIL, and docetaxel in preclinical models of HNSCC

OBJECTIVES: Head and neck squamous cell carcinoma (HNSCC) cells are resistant to cell death induced by Tumor Necrosis Factor ligands such as Tumor Necrosis Factor α (TNF) or TNF-Related Apoptosis-Inducing Ligand (TRAIL) and cytotoxic chemotherapies. Recently, genetic alterations in cell death pathwa...

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Publicado en:Laryngoscope
Main Authors: Eytan, Danielle F., Snow, Grace E., Carlson, Sophie G., Schiltz, Stephen, Chen, Zhong, Van Waes, Carter
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336212/
https://ncbi.nlm.nih.gov/pubmed/25431358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/lary.25056
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