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Targeting triple-negative breast cancers with the Smac-mimetic birinapant
Smac mimetics target inhibitor of apoptosis (IAP) proteins, thereby suppressing their function to facilitate tumor cell death. Here we have evaluated the efficacy of the preclinical Smac-mimetic compound A and the clinical lead birinapant on breast cancer cells. Both exhibited potent in vitro activi...
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| 出版年: | Cell Death Differ |
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| 主要な著者: | , , , , , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2020
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7492458/ https://ncbi.nlm.nih.gov/pubmed/32341449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-0541-0 |
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