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Combination effects of SMAC mimetic birinapant with TNFα, TRAIL, and docetaxel in preclinical models of HNSCC
OBJECTIVES: Head and neck squamous cell carcinoma (HNSCC) cells are resistant to cell death induced by Tumor Necrosis Factor ligands such as Tumor Necrosis Factor α (TNF) or TNF-Related Apoptosis-Inducing Ligand (TRAIL) and cytotoxic chemotherapies. Recently, genetic alterations in cell death pathwa...
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| Udgivet i: | Laryngoscope |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4336212/ https://ncbi.nlm.nih.gov/pubmed/25431358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/lary.25056 |
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