SMAC mimetic birinapant plus radiation eradicates human head and neck cancers with genomic amplifications of cell death genes FADD and BIRC2

Comparison of tumors from the Cancer Genome Atlas (TCGA) reveals that head and neck squamous cell carcinomas (HNSCC) harbor the most frequent genomic amplifications of Fas-associated death domain (FADD), with or without Baculovirus Inhibitor of Apoptosis repeat containing BIRC2 (cIAP1), affecting ~3...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Eytan, Danielle F., Snow, Grace E., Carlson, Sophie, Derakhshan, Adeeb, Saleh, Anthony, Schiltz, Stephen, Cheng, Hui, Mohan, Suresh, Cornelius, Shaleeka, Coupar, Jamie, Sowers, Anastasia L., Hernandez, Lidia, Mitchell, James B., Annunziata, Christina M., Chen, Zhong, Van Waes, Carter
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026594/
https://ncbi.nlm.nih.gov/pubmed/27469115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-3317
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