Evolution: A Guide to Perturb Protein Function and Networks

Por Lichtarge, Olivier, Wilkins, Angela
Publicado em 2010

A formal perturbation equation between genotype and phenotype determines the Evolutionary Action of protein-coding variations on fitness

Por Katsonis, Panagiotis, Lichtarge, Olivier
Publicado no Genome Res (2014)

Rapid detection of similarity in protein structure and function through contact metric distances

Por Lisewski, Andreas Martin, Lichtarge, Olivier
Publicado em 2006

Untangling complex networks: risk minimization in financial markets through accessible spin glass ground states

Por Lisewski, Andreas Martin, Lichtarge, Olivier
Publicado em 2010

PyETV: a PyMOL evolutionary trace viewer to analyze functional site predictions in protein complexes

Por Lua, Rhonald C., Lichtarge, Olivier
Publicado em 2010

REPURPOSING GERMLINE EXOMES OF THE CANCER GENOME ATLAS DEMANDS A CAUTIOUS APPROACH AND SAMPLE-SPECIFIC VARIANT FILTERING

Por KOIRE, AMANDA, KATSONIS, PANAGIOTIS, LICHTARGE, OLIVIER
Publicado no Pac Symp Biocomput (2016)

Protein Function Prediction: Towards Integration of Similarity Metrics

Por Erdin, Serkan, Lisewski, Andreas Martin, Lichtarge, Olivier
Publicado em 2011

COMPUTING THERAPY FOR PRECISION MEDICINE: COLLABORATIVE FILTERING INTEGRATES AND PREDICTS MULTI-ENTITY INTERACTIONS

Por REGENBOGEN, SAM, WILKINS, ANGELA D., LICHTARGE, OLIVIER
Publicado no Pac Symp Biocomput (2016)

HUMAN KINASES DISPLAY MUTATIONAL HOTSPOTS AT COGNATE POSITIONS WITHIN CANCER

Por GALLION, JONATHAN, WILKINS, ANGELA D., LICHTARGE, OLIVIER
Publicado no Pac Symp Biocomput (2016)

THE USE OF EVOLUTIONARY PATTERNS IN PROTEIN ANNOTATION

Por Wilkins, Angela, Bachman, Ben, Erdin, Serkan, Lichtarge, Olivier
Publicado em 2012

Evolutionary Trace for Prediction and Redesign of Protein Functional Sites

Por Wilkins, Angela, Erdin, Serkan, Lua, Rhonald, Lichtarge, Olivier
Publicado no Methods Mol Biol (2012)

Evolutionary Trace Annotation of Protein Function in the Structural Proteome

Por Erdin, Serkan, Ward, R. Matthew, Venner, Eric, Lichtarge, Olivier
Publicado em 2009

Function prediction from networks of local evolutionary similarity in protein structure

Por Erdin, Serkan, Venner, Eric, Lisewski, Andreas Martin, Lichtarge, Olivier
Publicado em 2013

A regulator of G protein signaling interaction surface linked to effector specificity

Por Sowa, Mathew E., He, Wei, Wensel, Theodore G., Lichtarge, Olivier
Publicado em 2000

Identification of functionally important residues/domains in membrane proteins using an evolutionary approach coupled with systematic mutational analysis

Por Rajagopalan, Lavanya, Pereira, Fred A., Lichtarge, Olivier, Brownell, William E.
Publicado em 2009

Functional Rescue of β(1)-Adrenoceptor Dimerization and Trafficking by Pharmacological Chaperones

Por Kobayashi, Hiroyuki, Ogawa, Koji, Yao, Rong, Lichtarge, Olivier, Bouvier, Michel
Publicado em 2009

Evolution-guided discovery and recoding of allosteric pathway specificity determinants in psychoactive bioamine receptors

Por Rodriguez, Gustavo J., Yao, Rong, Lichtarge, Olivier, Wensel, Theodore G.
Publicado em 2010

Cooperativity of Negative Autoregulation Confers Increased Mutational Robustness

Por Marciano, David C., Lua, Rhonald C., Herman, Christophe, Lichtarge, Olivier
Publicado no Phys Rev Lett (2016)

Determinants of Endogenous Ligand Specificity Divergence among Metabotropic Glutamate Receptors

Por Kang, Hye Jin, Wilkins, Angela D., Lichtarge, Olivier, Wensel, Theodore G.
Publicado no J Biol Chem (2015)

ETAscape: analyzing protein networks to predict enzymatic function and substrates in Cytoscape

Por Bachman, Benjamin J., Venner, Eric, Lua, Rhonald C., Erdin, Serkan, Lichtarge, Olivier
Publicado em 2012