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Determinants of Endogenous Ligand Specificity Divergence among Metabotropic Glutamate Receptors
To determine the structural origins of diverse ligand response specificities among metabotropic glutamate receptors (mGluRs), we combined computational approaches with mutagenesis and ligand response assays to identify specificity-determining residues in the group I receptor, mGluR1, and the group I...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4317032/ https://ncbi.nlm.nih.gov/pubmed/25519912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.622233 |
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