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Cooperativity of Negative Autoregulation Confers Increased Mutational Robustness
Negative autoregulation is universally found across organisms. In the bacterium Escherichia coli, transcription factors often repress their own expression to form a negative feedback network motif that enables robustness to changes in biochemical parameters. Here we present a simple phenomenological...
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| Publicado no: | Phys Rev Lett |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5152588/ https://ncbi.nlm.nih.gov/pubmed/27391757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1103/PhysRevLett.116.258104 |
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