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Negative feedback confers mutational robustness in yeast transcription factor regulation
Organismal fitness depends on the ability of gene networks to function robustly in the face of environmental and genetic perturbations. Understanding the mechanisms of this stability is one of the key aims of modern systems biology. Dissecting the basis of robustness to mutation has proven a particu...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3309721/ https://ncbi.nlm.nih.gov/pubmed/22355134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1116360109 |
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