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Evolutionary Trace for Prediction and Redesign of Protein Functional Sites
The evolutionary trace (ET) is the single most validated approach to identify protein functional determinants and to target mutational analysis, protein engineering and drug design to the most relevant sites of a protein. It applies to the entire proteome; its predictions come with a reliability sco...
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Publicado no: | Methods Mol Biol |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4892863/ https://ncbi.nlm.nih.gov/pubmed/22183528 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-465-0_3 |
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