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REPURPOSING GERMLINE EXOMES OF THE CANCER GENOME ATLAS DEMANDS A CAUTIOUS APPROACH AND SAMPLE-SPECIFIC VARIANT FILTERING

When seeking to reproduce results derived from whole-exome or genome sequencing data that could advance precision medicine, the time and expense required to produce a patient cohort make data repurposing an attractive option. The first step in repurposing is setting some quality baseline for the dat...

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Detalhes bibliográficos
Publicado no:Pac Symp Biocomput
Main Authors: KOIRE, AMANDA, KATSONIS, PANAGIOTIS, LICHTARGE, OLIVIER
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720392/
https://ncbi.nlm.nih.gov/pubmed/26776187
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