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A formal perturbation equation between genotype and phenotype determines the Evolutionary Action of protein-coding variations on fitness

The relationship between genotype mutations and phenotype variations determines health in the short term and evolution over the long term, and it hinges on the action of mutations on fitness. A fundamental difficulty in determining this action, however, is that it depends on the unique context of ea...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Genome Res
Päätekijät: Katsonis, Panagiotis, Lichtarge, Olivier
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory Press 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248321/
https://ncbi.nlm.nih.gov/pubmed/25217195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.176214.114
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