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Function prediction from networks of local evolutionary similarity in protein structure

BACKGROUND: Annotating protein function with both high accuracy and sensitivity remains a major challenge in structural genomics. One proven computational strategy has been to group a few key functional amino acids into templates and search for these templates in other protein structures, so as to t...

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Detalhes bibliográficos
Main Authors: Erdin, Serkan, Venner, Eric, Lisewski, Andreas Martin, Lichtarge, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3584919/
https://ncbi.nlm.nih.gov/pubmed/23514548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-14-S3-S6
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