Inositol, neural tube closure and the prevention of neural tube defects

Por Greene, Nicholas D.E., Leung, Kit‐Yi, Copp, Andrew J.
Publicado no Birth Defects Res (2017)

Quantitative analysis of myo-inositol in urine, blood and nutritional supplements by high-performance liquid chromatography tandem mass spectrometry

Por Leung, Kit-Yi, Mills, Kevin, Burren, Katie A., Copp, Andrew J., Greene, Nicholas D.E.
Publicado em 2011

Nucleotide precursors prevent folic acid-resistant neural tube defects in the mouse

Por Leung, Kit-Yi, De Castro, Sandra C.P., Savery, Dawn, Copp, Andrew J., Greene, Nicholas D.E.
Publicado em 2013

Inositol for the prevention of neural tube defects: a pilot randomised controlled trial

Por Greene, Nicholas D. E., Leung, Kit-Yi, Gay, Victoria, Burren, Katie, Mills, Kevin, Chitty, Lyn S., Copp, Andrew J.
Publicado no Br J Nutr (2016)

Inositol for prevention of neural tube defects: a pilot randomised controlled trial - CORRIGENDUM

Por Greene, Nicholas D. E., Leung, Kit-Yi, Gay, Victoria, Burren, Katie, Mills, Kevin, Chitty, Lyn S., Copp, Andrew J.
Publicado no Br J Nutr (2016)

Folate metabolite profiling of different cell types and embryos suggests variation in folate one-carbon metabolism, including developmental changes in human embryonic brain

Por Leung, Kit-Yi, De Castro, Sandra C. P., Cabreiro, Filipe, Gustavsson, Peter, Copp, Andrew J., Greene, Nicholas D. E.
Publicado em 2013

Neural tube defects induced by folate deficiency in mutant curly tail (Grhl3) embryos are associated with alteration in folate one-carbon metabolism but are unlikely to result from...

Por De Castro, Sandra CP, Leung, Kit-yi, Savery, Dawn, Burren, Katie, Rozen, Rima, Copp, Andrew J., Greene, Nicholas D.E.
Publicado em 2010

Lamin B1 Polymorphism Influences Morphology of the Nuclear Envelope, Cell Cycle Progression, and Risk of Neural Tube Defects in Mice

Por De Castro, Sandra C. P., Malhas, Ashraf, Leung, Kit-Yi, Gustavsson, Peter, Vaux, David J., Copp, Andrew J., Greene, Nicholas D. E.
Publicado em 2012

Protein deiminases: new players in the developmentally regulated loss of neural regenerative ability

Por Lange, Sigrun, Gögel, Stefanie, Leung, Kit-Yi, Vernay, Bertrand, Nicholas, Anthony P., Causey, Corey P., Thompson, Paul R., Greene, Nicholas D.E., Ferretti, Patrizia
Publicado no Dev Biol (2011)

Formate supplementation enhances folate-dependent nucleotide biosynthesis and prevents spina bifida in a mouse model of folic acid-resistant neural tube defects

Por Sudiwala, Sonia, De Castro, Sandra C.P., Leung, Kit-Yi, Brosnan, John T., Brosnan, Margaret E., Mills, Kevin, Copp, Andrew J., Greene, Nicholas D.E.
Publicado no Biochimie (2016)

Metformin Retards Aging in C. elegans by Altering Microbial Folate and Methionine Metabolism

Por Cabreiro, Filipe, Au, Catherine, Leung, Kit-Yi, Vergara-Irigaray, Nuria, Cochemé, Helena M., Noori, Tahereh, Weinkove, David, Schuster, Eugene, Greene, Nicholas D.E., Gems, David
Publicado em 2013

Glycine decarboxylase deficiency causes neural tube defects and features of non-ketotic hyperglycinemia in mice

Por Pai, Yun Jin, Leung, Kit-Yi, Savery, Dawn, Hutchin, Tim, Prunty, Helen, Heales, Simon, Brosnan, Margaret E., Brosnan, John T., Copp, Andrew J., Greene, Nicholas D.E.
Publicado no Nat Commun (2015)

β-Actin regulates platelet nitric oxide synthase 3 activity through interaction with heat shock protein 90

Por Ji, Yong, Ferracci, Géraldine, Warley, Alice, Ward, Malcolm, Leung, Kit-Yi, Samsuddin, Salma, Lév̂que, Christian, Queen, Lindsay, Reebye, Vikash, Pal, Pallavi, Gkaliagkousi, Eugenia, Seager, Michael, Ferro, Albert
Publicado em 2007

High folic acid consumption leads to pseudo-MTHFR deficiency, altered lipid metabolism, and liver injury in mice(1)(2)(3)(4)(5)

Por Christensen, Karen E, Mikael, Leonie G, Leung, Kit-Yi, Lévesque, Nancy, Deng, Liyuan, Wu, Qing, Malysheva, Olga V, Best, Ana, Caudill, Marie A, Greene, Nicholas DE, Rozen, Rima
Publicado no Am J Clin Nutr (2015)

Tyrosine Phosphorylation of Tau by the Src Family Kinases Lck and Fyn

Por Bird Ian N, Price Caroline, Ward Malcolm A, Byers Helen L, Leung Kit-Yi, Derkinderen Pascal, Scales Timothy ME, Perera Timothy, Kellie Stuart, Williamson Ritchie, Anderton Brian H, Reynolds C Hugh
Publicado em 2011-01-01

Tyrosine Phosphorylation of Tau by the Src Family Kinases Lck and Fyn

Por Scales, Timothy ME, Derkinderen, Pascal, Leung, Kit-Yi, Byers, Helen L, Ward, Malcolm A, Price, Caroline, Bird, Ian N, Perera, Timothy, Kellie, Stuart, Williamson, Ritchie, Anderton, Brian H, Reynolds, C Hugh
Publicado em 2011

High dietary folate in pregnant mice leads to pseudo-MTHFR deficiency and altered methyl metabolism, with embryonic growth delay and short-term memory impairment in offspring

Por Bahous, Renata H., Jadavji, Nafisa M., Deng, Liyuan, Cosín-Tomás, Marta, Lu, Jessica, Malysheva, Olga, Leung, Kit-Yi, Ho, Ming-Kai, Pallàs, Mercè, Kaliman, Perla, Greene, Nicholas D.E., Bedell, Barry J., Caudill, Marie A., Rozen, Rima
Publicado no Hum Mol Genet (2017)

A role of matrix metalloproteinase-8 in atherosclerosis

Por Laxton, Ross C., Hu, Yanhua, Duchene, Johan, Zhang, Feng, Zhang, Zhongyi, Leung, Kit-Yi, Xiao, Qingzhong, Scotland, Ramona S., Hodgkinson, Conrad P., Smith, Katherine, Willeit, Johann, López-Otín, Carlos, Simpson, Iain A., Kiechl, Stefan, Ahluwalia, Amrita, Xu, Qingbo, Ye, Shu
Publicado em 2009

Host-Microbe Co-metabolism Dictates Cancer Drug Efficacy in C. elegans

Por Scott, Timothy A., Quintaneiro, Leonor M., Norvaisas, Povilas, Lui, Prudence P., Wilson, Matthew P., Leung, Kit-Yi, Herrera-Dominguez, Lucia, Sudiwala, Sonia, Pessia, Alberto, Clayton, Peter T., Bryson, Kevin, Velagapudi, Vidya, Mills, Philippa B., Typas, Athanasios, Greene, Nicholas D.E., Cabreiro, Filipe
Publicado no Cell (2017)

Mutations in genes encoding the glycine cleavage system predispose to neural tube defects in mice and humans

Por Narisawa, Ayumi, Komatsuzaki, Shoko, Kikuchi, Atsuo, Niihori, Tetsuya, Aoki, Yoko, Fujiwara, Kazuko, Tanemura, Mitsuyo, Hata, Akira, Suzuki, Yoichi, Relton, Caroline L., Grinham, James, Leung, Kit-Yi, Partridge, Darren, Robinson, Alexis, Stone, Victoria, Gustavsson, Peter, Stanier, Philip, Copp, Andrew J., Greene, Nicholas D.E., Tominaga, Teiji, Matsubara, Yoichi, Kure, Shigeo
Publicado em 2012