A role of matrix metalloproteinase-8 in atherosclerosis

RATIONALE: Atherosclerotic lesions express matrix metalloproteinase-8 (MMP8) which possesses proteolytic activity on matrix proteins particularly fibrillar collagens and on non-matrix proteins such as angiotensin I (Ang I). OBJECTIVE: We studied whether MMP8 plays a role in atherogenesis. METHODS AN...

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Detalhes bibliográficos
Main Authors: Laxton, Ross C., Hu, Yanhua, Duchene, Johan, Zhang, Feng, Zhang, Zhongyi, Leung, Kit-Yi, Xiao, Qingzhong, Scotland, Ramona S., Hodgkinson, Conrad P., Smith, Katherine, Willeit, Johann, López-Otín, Carlos, Simpson, Iain A., Kiechl, Stefan, Ahluwalia, Amrita, Xu, Qingbo, Ye, Shu
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853782/
https://ncbi.nlm.nih.gov/pubmed/19745165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.200279
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