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Nucleotide precursors prevent folic acid-resistant neural tube defects in the mouse

Closure of the neural tube during embryogenesis is a crucial step in development of the central nervous system. Failure of this process results in neural tube defects, including spina bifida and anencephaly, which are among the most common birth defects worldwide. Maternal use of folic acid suppleme...

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Detalhes bibliográficos
Main Authors: Leung, Kit-Yi, De Castro, Sandra C.P., Savery, Dawn, Copp, Andrew J., Greene, Nicholas D.E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754462/
https://ncbi.nlm.nih.gov/pubmed/23935126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awt209
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