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Neural tube defects induced by folate deficiency in mutant curly tail (Grhl3) embryos are associated with alteration in folate one-carbon metabolism but are unlikely to result from diminished methylation
BACKGROUND: Folate one-carbon metabolism has been implicated as a determinant of susceptibility to neural tube defects (NTDs), owing to the preventive effect of maternal folic acid supplementation and the higher risk associated with markers of diminished folate status. METHODS: Folate one-carbon met...
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Auteurs principaux: | , , , , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
2010
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3634156/ https://ncbi.nlm.nih.gov/pubmed/20589880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdra.20690 |
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