Lamin B1 Polymorphism Influences Morphology of the Nuclear Envelope, Cell Cycle Progression, and Risk of Neural Tube Defects in Mice

Neural tube defects (NTDs), including spina bifida and anencephaly, are common birth defects whose complex multigenic causation has hampered efforts to delineate their molecular basis. The effect of putative modifier genes in determining NTD susceptibility may be investigated in mouse models, partic...

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Detalhes bibliográficos
Main Authors: De Castro, Sandra C. P., Malhas, Ashraf, Leung, Kit-Yi, Gustavsson, Peter, Vaux, David J., Copp, Andrew J., Greene, Nicholas D. E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499363/
https://ncbi.nlm.nih.gov/pubmed/23166514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003059
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