Cargando...

Stress-induced release of Oct-1 from the nuclear envelope is mediated by JNK phosphorylation of lamin B1

The nuclear lamina can bind and sequester transcription factors (TFs), a function lost if the lamina is abnormal, with missing or mutant lamin proteins. We now show that TF sequestration is not all-or-nothing, but a dynamic physiological response to external signals. We show that the binding of the...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:PLoS One
Autores principales: Boubriak, Ivan I., Malhas, Ashraf N., Drozdz, Marek M., Pytowski, Lior, Vaux, David J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5443517/
https://ncbi.nlm.nih.gov/pubmed/28542436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177990
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!