Mitochondrial signaling in cell death via the Bcl-2 family

Por Leibowitz, Brian, Yu, Jian
Publicado em 2010

Growth factors protect intestinal stem cells from radiation-induced apoptosis by suppressing PUMA through the PI3K/AKT/p53 axis

Por Qiu, Wei, Leibowitz, Brian, Zhang, Lin, Yu, Jian
Publicado em 2009

PUMA-mediated apoptosis drives chemical hepatocarcinogenesis in mice

Por Qiu, Wei, Wang, Xinwei, Leibowitz, Brian, Yang, Wancai, Zhang, Lin, Yu, Jian
Publicado em 2011

Uncoupling p53 functions in radiation-induced intestinal damage via PUMA and p21

Por Leibowitz, Brian J., Qiu, Wei, Liu, Hongtao, Cheng, Tao, Zhang, Lin, Yu, Jian
Publicado em 2011

Inhibition of CDK4/6 protects against radiation-induced intestinal injury in mice

Por Wei, Liang, Leibowitz, Brian J., Wang, Xinwei, Epperly, Michael, Greenberger, Joel, Zhang, Lin, Yu, Jian
Publicado no J Clin Invest (2016)

Ionizing irradiation induces acute haematopoietic syndrome and gastrointestinal syndrome independently in mice

Por Leibowitz, Brian J., Wei, Liang, Zhang, Lin, Ping, Xiaochun, Epperly, Michael, Greenberger, Joel, Cheng, Tao, Yu, Jian
Publicado no Nat Commun (2014)

Early prediction of cancer progression by depth-resolved nanoscale maps of nuclear architecture from unstained tissue specimens

Por Uttam, Shikhar, Pham, Hoa V., LaFace, Justin, Leibowitz, Brian, Yu, Jian, Brand, Randall E., Hartman, Douglas J., Liu, Yang
Publicado no Cancer Res (2015)

The GS-nitroxide JP4-039 improves intestinal barrier and stem cell recovery in irradiated mice

Por Wei, Liang, Leibowitz, Brian J., Epperly, Michael, Bi, Cheng, Li, Allen, Steinman, Justin, Wipf, Peter, Li, Song, Zhang, Lin, Greenberger, Joel, Yu, Jian
Publicado no Sci Rep (2018)

BID mediates selective killing of APC-deficient cells in intestinal tumor suppression by nonsteroidal antiinflammatory drugs

Por Leibowitz, Brian, Qiu, Wei, Buchanan, Monica E., Zou, Fangdong, Vernon, Philip, Moyer, Mary P., Yin, Xiao-Ming, Schoen, Robert E., Yu, Jian, Zhang, Lin
Publicado no Proc Natl Acad Sci U S A (2014)

Chemoprevention by nonsteroidal anti-inflammatory drugs eliminates oncogenic intestinal stem cells via SMAC-dependent apoptosis

Por Qiu, Wei, Wang, Xinwei, Leibowitz, Brian, Liu, Hongtao, Barker, Nick, Okada, Hitoshi, Oue, Naohide, Yasui, Wataru, Clevers, Hans, Schoen, Robert E., Yu, Jian, Zhang, Lin
Publicado em 2010

γPNA FRET Pair Miniprobes for Quantitative Fluorescent In Situ Hybridization to Telomeric DNA in Cells and Tissue

Por Orenstein, Alexander, Berlyoung, April S., Rastede, Elizabeth E., Pham, Ha H., Fouquerel, Elise, Murphy, Connor T., Leibowitz, Brian J., Yu, Jian, Srivastava, Tumul, Armitage, Bruce A., Opresko, Patricia L.
Publicado no Molecules (2017)

Targeting p53-dependent stem cell loss for intestinal chemoprotection

Por Leibowitz, Brian J., Yang, Liheng, Wei, Liang, Buchanan, Monica E., Rachid, Madani, Parise, Robert A., Beumer, Jan H., Eiseman, Julie L., Schoen, Robert E., Zhang, Lin, Yu, Jian
Publicado no Sci Transl Med (2018)

Pharmacologic ATM but not ATR kinase inhibition abrogates p21-dependent G1 arrest and promotes gastrointestinal syndrome after total body irradiation

Por Vendetti, Frank P., Leibowitz, Brian J., Barnes, Jennifer, Schamus, Sandy, Kiesel, Brian F., Abberbock, Shira, Conrads, Thomas, Clump, David Andy, Cadogan, Elaine, O’Connor, Mark J., Yu, Jian, Beumer, Jan H., Bakkenist, Christopher J.
Publicado no Sci Rep (2017)

Pharmacologically blocking p53-dependent apoptosis protects intestinal stem cells and mice from radiation

Por Wang, Xinwei, Wei, Liang, Cramer, Julie M., Leibowitz, Brian J., Judge, Colleen, Epperly, Michael, Greenberger, Joel, Wang, Fengchao, Li, Linheng, Stelzner, Matthias G., Dunn, James C. Y., Martin, Martin G., Lagasse, Eric, Zhang, Lin, Yu, Jian
Publicado no Sci Rep (2015)