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PUMA-mediated apoptosis drives chemical hepatocarcinogenesis in mice

Hepatocyte death and proliferation contribute to hepatocellular carcinoma development following carcinogen exposure or chronic liver inflammation. However, the role and the molecular targets of hepatocyte death in relation to compensatory proliferation remain to be fully characterized. In this study...

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Bibliografiske detaljer
Main Authors: Qiu, Wei, Wang, Xinwei, Leibowitz, Brian, Yang, Wancai, Zhang, Lin, Yu, Jian
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3184207/
https://ncbi.nlm.nih.gov/pubmed/21725994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24516
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