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PUMA-mediated apoptosis drives chemical hepatocarcinogenesis in mice

Hepatocyte death and proliferation contribute to hepatocellular carcinoma development following carcinogen exposure or chronic liver inflammation. However, the role and the molecular targets of hepatocyte death in relation to compensatory proliferation remain to be fully characterized. In this study...

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Autors principals: Qiu, Wei, Wang, Xinwei, Leibowitz, Brian, Yang, Wancai, Zhang, Lin, Yu, Jian
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3184207/
https://ncbi.nlm.nih.gov/pubmed/21725994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24516
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