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PUMA-mediated apoptosis drives chemical hepatocarcinogenesis in mice

Hepatocyte death and proliferation contribute to hepatocellular carcinoma development following carcinogen exposure or chronic liver inflammation. However, the role and the molecular targets of hepatocyte death in relation to compensatory proliferation remain to be fully characterized. In this study...

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Detalhes bibliográficos
Main Authors: Qiu, Wei, Wang, Xinwei, Leibowitz, Brian, Yang, Wancai, Zhang, Lin, Yu, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3184207/
https://ncbi.nlm.nih.gov/pubmed/21725994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24516
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