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p53 independent induction of PUMA mediates intestinal apoptosis in response to ischaemia–reperfusion

BACKGROUND: The small intestine is highly sensitive to ischaemia–reperfusion (I/R) induced injury which is associated with high morbidity and mortality. Apoptosis, or programmed cell death, is a major mode of cell death occurring during I/R induced injury. However, the mechanisms by which I/R cause...

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Autori principali: Wu, Bin, Qiu, Wei, Wang, Peng, Yu, Hui, Cheng, Tao, Zambetti, Gerard P, Zhang, Lin, Yu, Jian
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Group 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1942137/
https://ncbi.nlm.nih.gov/pubmed/17127703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2006.101683
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