PUMA-mediated intestinal epithelial apoptosis contributes to ulcerative colitis in humans and mice

Intestinal epithelial cell (IEC) apoptosis contributes to the development of ulcerative colitis (UC), an inflammatory bowel disease (IBD) that affects the colon and rectum. Therapies that target the inflammatory cytokine TNF have been found to inhibit IEC apoptosis in patients with IBD, although the...

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Dades bibliogràfiques
Autors principals: Qiu, Wei, Wu, Bin, Wang, Xinwei, Buchanan, Monica E., Regueiro, Miguel D., Hartman, Douglas J., Schoen, Robert E., Yu, Jian, Zhang, Lin
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083802/
https://ncbi.nlm.nih.gov/pubmed/21490394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI42917
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