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PUMA-mediated intestinal epithelial apoptosis contributes to ulcerative colitis in humans and mice
Intestinal epithelial cell (IEC) apoptosis contributes to the development of ulcerative colitis (UC), an inflammatory bowel disease (IBD) that affects the colon and rectum. Therapies that target the inflammatory cytokine TNF have been found to inhibit IEC apoptosis in patients with IBD, although the...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3083802/ https://ncbi.nlm.nih.gov/pubmed/21490394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI42917 |
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