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PUMA Suppresses Intestinal Tumorigenesis in Mice

Defective apoptosis contributes to tumorigenesis, although the critical molecular targets remain to be fully characterized. PUMA, a BH3-only protein essential for p53-dependent apoptosis, has been shown to suppress lymphomagenesis. In this study, we investigated the role of PUMA in intestinal tumori...

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Detalhes bibliográficos
Main Authors: Qiu, Wei, Carson-Walter, Eleanor B., Kuan, Shih Fan, Zhang, Lin, Yu, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872079/
https://ncbi.nlm.nih.gov/pubmed/19491259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-0262
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