ATR kinase inhibition induces unscheduled origin firing through a Cdc7-dependent association between GINS and And-1

Por Moiseeva, Tatiana, Hood, Brian, Schamus, Sandy, O’Connor, Mark J., Conrads, Thomas P., Bakkenist, Christopher J.
Publicado no Nat Commun (2017)

Parp1 activation in mouse embryonic fibroblasts promotes Pol β-dependent cellular hypersensitivity to alkylation damage

Por Jelezcova, Elena, Trivedi, Ram N., Wang, Xiao-hong, Tang, Jiang-bo, Brown, Ashley R., Goellner, Eva M., Schamus, Sandy, Fornsaglio, Jamie L., Sobol, Robert W.
Publicado em 2010

HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase β

Por Fang, Qingming, Inanc, Burcu, Schamus, Sandy, Wang, Xiao-hong, Wei, Leizhen, Brown, Ashley R., Svilar, David, Sugrue, Kelsey F., Goellner, Eva M., Zeng, Xuemei, Yates, Nathan A., Lan, Li, Vens, Conchita, Sobol, Robert W.
Publicado no Nat Commun (2014)

Pharmacologic ATM but not ATR kinase inhibition abrogates p21-dependent G1 arrest and promotes gastrointestinal syndrome after total body irradiation

Por Vendetti, Frank P., Leibowitz, Brian J., Barnes, Jennifer, Schamus, Sandy, Kiesel, Brian F., Abberbock, Shira, Conrads, Thomas, Clump, David Andy, Cadogan, Elaine, O’Connor, Mark J., Yu, Jian, Beumer, Jan H., Bakkenist, Christopher J.
Publicado no Sci Rep (2017)