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The GS-nitroxide JP4-039 improves intestinal barrier and stem cell recovery in irradiated mice
Total body irradiation (TBI) leads to dose- and tissue-specific lethality. In the current study, we demonstrate that a mitochondrion-targeted nitroxide JP4-039 given once 24 hours after 9–10 Gy TBI significantly improves mouse survival, and the recovery of intestinal barrier, differentiation and ste...
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| 出版年: | Sci Rep |
|---|---|
| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5794877/ https://ncbi.nlm.nih.gov/pubmed/29391546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20370-9 |
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