Fanconi Anemia Mouse Genotype-specific Mitigation of Total Body Irradiation by GS-Nitroxide JP4-039

Background/Aim: Radiation mitigator, GS-nitroxide, JP4-039, was evaluated for mitigation of total body irradiation (TBI) in Fanconi anemia (FA) Fancd2(−/−) (129/Sv), Fancg(−/−) (B6), and Fanca(−/−) (129/Sv) mice. Materials and Methods: JP4-039 dissolved in 30% 2-hydroxypropyl-β-cyclodextrin was inje...

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Publicat a:In Vivo
Autors principals: EPPERLY, MICHAEL W., FISHER, RENEE, ZHANG, XICHEN, HOU, WEN, SHIELDS, DONNA, WIPF, PETER, WANG, HONG, THERMOZIER, STEPHANIE, GREENBERGER, JOEL S.
Format: Artigo
Idioma:Inglês
Publicat: International Institute of Anticancer Research 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6984088/
https://ncbi.nlm.nih.gov/pubmed/31882460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/invivo.11742
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