Induction of TGF-β by Irradiation or Chemotherapy in Fanconi Anemia (FA) Mouse Bone Marrow Ιs Modulated by Small Molecule Radiation Mitigators JP4-039 and MMS350

Background/Aim: Total-body irradiation and/or administration of chemotherapy drugs in bone marrow transplantation induce cytokines that can suppress engraftment. Fanconi Anemia (FA) patients have a hyperactive responsiveness to the inhibitory cytokine, transforming growth factor-beta (TGF-β). Small...

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Bibliografske podrobnosti
izdano v:In Vivo
Main Authors: EPPERLY, MICHAEL W, RHIEU, BYUNG-HAN, FRANICOLA, DARCY, DIXON, TRACY, CAO, SHAONAN, ZHANG, XICHEN, SHIELDS, DONNA, WANG, HONG, WIPF, PETER, GREENBERGER, JOEL S
Format: Artigo
Jezik:Inglês
Izdano: International Institute of Anticancer Research 2017
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5411740/
https://ncbi.nlm.nih.gov/pubmed/28358695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/invivo.11040
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