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Continuous One Year Oral Administration of the Radiation Mitigator, MMS350, after Total-Body Irradiation, Restores Bone Marrow Stromal Cell Proliferative Capacity and Reduces Senescence in Fanconi Anemia (Fanca(−/−)) Mice
We quantitated age-related accumulation of senescent cells in irradiated Fanconi anemia (FA) (Fanca(−/−)) mouse cell lines in vitro and monitored the effect of continuous administration (via drinking water) of the water-soluble radiation mitigator, MMS350, on tissues in vivo over one year after 7.5...
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| Izdano u: | Radiat Res |
|---|---|
| Glavni autori: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2018
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6388094/ https://ncbi.nlm.nih.gov/pubmed/30499383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR15199.1 |
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